7 Reviews

DP450 Iontophoresis Machine Package



Want to treat excessive sweating in the least amount of time? Use the DP450’s direct current (DC) setting. Rather maximize comfort? Use the DP450’s pulsed current (PC) setting. No matter your preference, the DP450 iontophoresis machine package includes everything you need to effectively treat excessive sweating (hyperhidrosis) in your hands and feet.

About the DP450 Iontophoresis Machine Package

Will my insurance cover it?

  • The DP450 is FDA CLEARED. This clearance is essential because insurance companies will not cover non-FDA approved or cleared devices.
  • We encourage our customers to submit to their insurance for reimbursement after purchase. Check out our Insurance Reimbursement Guide here.


  • Switchable between Direct or Pulsed Current to suit your comfort level—What’s the difference?
  • Anti Shock Electronics (ASE©) protects from the electric fence effect (unpleasant shocking)—What is ASE©?
  • Measures resistance/current through dryness in skin and automatically adjusts current up to the desired level (will operate at lower level if higher level is not necessary)
  • Can be used in clinical or home settings
  • Robust/durable construction

What’s in the box? (Everything you need for hands and feet treatment)

  • 1 Hidrex DP450 tapwater iontophoresis (TWI) module
  • US Type A plug AC Adapter (unless Type C is requested)
  • 1 carrying case (sides can be separated and used as treatment trays)
  • 1 pair of 4 mm thick connection cables
  • 1 pair of cotton towels
  • Manual & Quick Set Up Guide
  • 2 aluminum electrode plates (used for hands and feet treatment)

How do I order the DP450?

  • This product needs a prescription from your doctor in order to fulfill the order, so buy now and then email your prescription to [email protected].
  • Having difficulty obtaining a prescription? We can help, so get in touch.

What are the differences between the DP450 and the DVP1000?

DP450 (GP450) tap water iontophoresis machine for hyperhidrosisDVP1000 tap water iontophoresis device for hyperhidrosis
Direct Current (DC)YesYes
Pulsed Current (PC)YesYes
Variable Pulsed Current (VPC)NoYes
Available pulse-widths (in %)50 or 10050, 60, 70, 80, 90, 100
Adjustable voltage0-40V0-60V
Max current30mA35mA
Measurement unit on displayVolts onlyVolts or amps
Power supply110-240V~; 50-60Hz110-240V~; 50-60Hz
# of programmable preset profiles13
Built-in timer range0-59 minutes0-59 minutes
Displays remaining timeYesYes
Anti Shock Electronics (ASE©)YesYes
Over-treatment protectionYesYes
Active current indicator LEDYesYes
Module size (W x D x H)7.5" x 5.4" x 2"7.5" x 5.4" x 2"
Module weight1lb.1lb.

Additional information

Weight 1 lbs
Dimensions 5.4 × 7.5 × 2 in

Two (2) year warranty of TWI module

7 reviews for DP450 Iontophoresis Machine Package

  1. Sandeep Soma (verified owner)

    I cannot say in words how happy I am while writing this review. I would like to thank all the people involved in “A to Z” of Hidrex DP450 machine. The process of Iontophoresis using DP450 has significantly reduced sweating on my palms. Now, my hands are dry and I feel more confident while doing my day to day activities. I am currently in my 9th session and I am sure by the end of 2 week regime, I will get 100% results. Thank you Hidrex and Team for delivering such a wonderful product. Wish I could blow your star rating above 5.

  2. Ann

    I have been using this every day since 3 weeks. I can’t believe that it actually works. Feels so good to finally have dry hands. I am going to continue using it for another few weeks and get my feets dry as well. I was really confused between the 2 products offered by Hidrex but this worked just fine. They also provide an option to use your FSA to buy this product which was really helpful considering the cost of the product. It is easy to set up and use. Highly recommended.

  3. Mel (verified owner)

    This device has improved my quality of life so much. It’s so wonderful to no longer fear handshakes. For many years I tried other devices, topical solutions, and prescription medications, and none came near to giving me the results of the Hidrex machine. I was a little nervous about investing in it, but now I am so glad that I did, it was completely worth it. The machine itself is easy to use and it’s great that it doesn’t require batteries that need replaced frequently like some others. Also customer service was extremely helpful and always available for any questions I had. For anyone out there with hyperhidrosis wondering if they should invest in this device, I would 100 percent recommend that you do! It works!

  4. Adam

    The device is great, easy to use, and it works ! Thanks to Hidrex for an amazing customer service. I am really happy with my purchase !

  5. Emma

    I bought this machine for palmar hyperhidrosis, and am absolutely amazed by the results. I have been using it for a little over two months now and am down to two 15-minute treatments per week with no problems of sweaty hands for the last 4 weeks or so. I am completing my first physical therapy clinical (which involves a lot of hands-on work) and have no reservations related to sweaty palms. Read the user manual before setting up as it gives some helpful information regarding settings and rotating the plates. Customer service was fantastic through Hidrex; timely responses and I always spoke to the same helpful rep – Chris, who even helped me find the correct insurance paperwork. I failed several other topical treatments before iontophoresis. I would definitely recommend this iontophoresis machine!

  6. Dave (verified owner)

    This Hidrex machine is top notch. I am absolutely blown away from my results. NEVER can I remember having dry hands or ever having to use lotion on my hands because they were always sweaty. It is an amazing feeling. As far as this machine goes – It’s easy to setup and use. I never was confused or had any problems with device and instructions. Customer service was outstanding – quick email replies and even a phone call to me when I had other questions. Once again, I’m so happy with everything, can’t be more excited and pleased. This works – it will for you too. Just buy it – it’s worth double the price. Thanks Hidrex!

  7. Brian

    Changed my life! Great customer service. Used the face-mask for my forehead although I did end up placing the electrode sockets on the forehead area – I now almost never have any sweating problems. Highly recommended for anyone with any type of hyperhidrosis. If it helped me (which I never thought anything could help my severe condition) it can help you.

Add a review

Your email address will not be published. Required fields are marked *