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DP450 Underarms Iontophoresis Machine

(7 customer reviews)


(includes everything you need to treat your underarms—just add water!)

Maximize comfort or efficiency with 2 current types
Maximize comfort or efficiency with 2 current types
German-engineered over 4+ decades
German-engineered across 4+ decades
60-day money-back guarantee
60-day money-back guarantee
96% success rate (only 4% request a refund, and most who do exchange it for the DVP1000 Hands & Feet)
96% satisfaction rate (only 4% request a refund, and most who do exchange it for the DVP1000)
"Just buy it – it’s worth double the price. Thanks Hidrex!"
— Dave

About the DP450 Underarms.


Ready to stop excessive underarm sweat? The DP450 Underarms iontophoresis machine includes everything you need to make it happen. Its direct current (DC) and pulsed current (PC) options empower you to tailor your treatment to your liking. Need to treat your hands & feet, too? Check out the DVP1000 Ultimate.


  • Switchable between Direct or Pulsed Current to suit your comfort level
  • Anti-Shock Electronics (ASE©) protects from the electric fence effect (unpleasant shocking)
  • Measures resistance/current through dryness in skin and automatically adjusts current up to the desired level (will operate at lower level if higher level is not necessary)
  • Can be used in clinical or home settings
  • Robust, durable construction

What’s in the box? (Everything you need to treat your underarms)

  • 1 Hidrex DP450 tapwater iontophoresis (TWI) module
  • US Type A plug AC Adapter (unless Type C is requested)
  • 1 carrying case (sides can be separated and used as treatment trays)
  • 1 pair of 4 mm thick connection cables
  • 1 pair of cotton towels
  • Manual & Quick Setup Guide
  • Set of 2 electrodes and 2 pads for axillary (underarm) iontophoresis treatment

Will my insurance cover it?


Because all Hidrex USA devices are FDA cleared, many insurance companies issue reimbursements for Hidrex USA iontophoresis machines. Want to know more? See our insurance reimbursement guide.

Can I order without a prescription?

For U.S. customers, we need an Rx on file to comply with our FDA Compliance Policy. So, you may order it, but we will need to have a prescription on file before we can ship it. If you don’t have one, we can easily help you get one, as we work with physicians that do quick and easy video calls to help with this. All non-U.S. customers may purchase without an Rx.

Additional information

Weight 1 lbs
Dimensions 5.4 × 7.5 × 2 in

Two (2) year warranty of TWI module

7 reviews for DP450 Underarms Iontophoresis Machine

  1. Brian

    Changed my life! Great customer service. Used the face-mask for my forehead although I did end up placing the electrode sockets on the forehead area – I now almost never have any sweating problems. Highly recommended for anyone with any type of hyperhidrosis. If it helped me (which I never thought anything could help my severe condition) it can help you.

  2. Dave (verified owner)

    This Hidrex machine is top notch. I am absolutely blown away from my results. NEVER can I remember having dry hands or ever having to use lotion on my hands because they were always sweaty. It is an amazing feeling. As far as this machine goes – It’s easy to setup and use. I never was confused or had any problems with device and instructions. Customer service was outstanding – quick email replies and even a phone call to me when I had other questions. Once again, I’m so happy with everything, can’t be more excited and pleased. This works – it will for you too. Just buy it – it’s worth double the price. Thanks Hidrex!

  3. Emma

    I bought this machine for palmar hyperhidrosis, and am absolutely amazed by the results. I have been using it for a little over two months now and am down to two 15-minute treatments per week with no problems of sweaty hands for the last 4 weeks or so. I am completing my first physical therapy clinical (which involves a lot of hands-on work) and have no reservations related to sweaty palms. Read the user manual before setting up as it gives some helpful information regarding settings and rotating the plates. Customer service was fantastic through Hidrex; timely responses and I always spoke to the same helpful rep – Chris, who even helped me find the correct insurance paperwork. I failed several other topical treatments before iontophoresis. I would definitely recommend this iontophoresis machine!

  4. Adam

    The device is great, easy to use, and it works ! Thanks to Hidrex for an amazing customer service. I am really happy with my purchase !

  5. Mel (verified owner)

    This device has improved my quality of life so much. It’s so wonderful to no longer fear handshakes. For many years I tried other devices, topical solutions, and prescription medications, and none came near to giving me the results of the Hidrex machine. I was a little nervous about investing in it, but now I am so glad that I did, it was completely worth it. The machine itself is easy to use and it’s great that it doesn’t require batteries that need replaced frequently like some others. Also customer service was extremely helpful and always available for any questions I had. For anyone out there with hyperhidrosis wondering if they should invest in this device, I would 100 percent recommend that you do! It works!

  6. Ann

    I have been using this every day since 3 weeks. I can’t believe that it actually works. Feels so good to finally have dry hands. I am going to continue using it for another few weeks and get my feets dry as well. I was really confused between the 2 products offered by Hidrex but this worked just fine. They also provide an option to use your FSA to buy this product which was really helpful considering the cost of the product. It is easy to set up and use. Highly recommended.

  7. Sandeep Soma (verified owner)

    I cannot say in words how happy I am while writing this review. I would like to thank all the people involved in “A to Z” of Hidrex DP450 machine. The process of Iontophoresis using DP450 has significantly reduced sweating on my palms. Now, my hands are dry and I feel more confident while doing my day to day activities. I am currently in my 9th session and I am sure by the end of 2 week regime, I will get 100% results. Thank you Hidrex and Team for delivering such a wonderful product. Wish I could blow your star rating above 5.

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